Uncommon contributors to ems and subsequent hyperinsulinemia are iron overload and ovarian abnormalities in some mares.
Iron excess and laminitis.
Excess iron is a much greater concern in horses because free iron ions fe2 act as oxidants causing damage to dna cell membranes and other structures.
Digestive upsets due to grain overload such as excess grain fruit or snacks or abrupt changes in diet.
In clue like fashion i m declaring the cause of my six horses laminitis over the last 18 years as an excess intake of iron from weeds trace mineral blocks and well water leading to insulin resistance and the insulin form of laminitis.
High levels of iron intake have also been associated with insulin resistance and laminitis in horses.
Dietary iron is thought by some to contribute to the incidence of laminitis in horses with serum ferritin starting to be used as the measure of iron status.
This can occur in equine metabolic syndrome ems and cushing s disorder ppid.
Iron deficiency anemia is rare and too much iron can potentially lead to laminitis as well as create an imbalance with other minerals.
Iron is toxic to the liver hepatotoxic and vets have reported that excessive iron deposition in the liver is a common finding in liver biopsies from older horses.
Iron overload symptoms in horses include coat changes of bleaching and red ends on dark manes and tails often hoof issues such as laminitis and abscessing.
This study linked iron status to insulin resistance ir in horses.
Furthermore forages pasture hay hay pellets or cubes are already high in iron making supplementation unnecessary and possibly dangerous.
Dan pitzen a water expert in ohio published a report several years ago titled.
These include coat changes of bleaching and red ends on dark manes and tails often hoof issues such as laminitis and abscessing.
It is estimated that 80 percent of all laminitis cases are due to endocrine dysfunction specifically excess insulin in the blood.
Although laminitis occurs in the feet the underlying cause is often a disturbance elsewhere in the horse s body.
I nerida don t know if this is the case but in reading human literature it seems the relationship between serum ferritin and inflammation is a bit of a case of chicken or the egg.
Iron overload symptoms in horses are likely a combination of direct iron effects and induced secondary deficiencies of other minerals.
